Myasthenia gravis: Protective effect of ipratropiumbromide (atrovent®) on airways obstruction caused by edrophonium chloride (tensilon®)

I. Szathmáry, P. Magyar, A. Szobor

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The preventive effect of Atrovent® Dosier-Aerosol on the airway flow resistance (Raw) caused by Tensilon® was studied on 10 patients suffering from myasthenia gravis. Atrovent completely prevented the increase of Raw in 8 cases and considerably decreased it in 2 cases. The measure of the reaction observed may be influenced by the intensity of the cholinergic symptoms occurring on administration of Tensilon as well as by the magnitude of the initial Raw value. No side-effect which may be attributed to the administration of Atrovent could be observed, the substance did not increase the myasthenic symptoms. According to the study. Atrovent is a suitable medicine for the prevention of airway obstruction caused by Tensilon.

Original languageEnglish
Pages (from-to)56-61
Number of pages6
JournalEuropean Neurology
Volume20
Issue number1
DOIs
Publication statusPublished - 1981

Fingerprint

Edrophonium
Ipratropium
Myasthenia Gravis
Airway Obstruction
Airway Resistance
Muscle Weakness
Aerosols
Cholinergic Agents
Medicine

Keywords

  • Airway obstruction
  • Edrophonium chloride
  • Ipratropium - bromide
  • Myasthenia gravis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Myasthenia gravis : Protective effect of ipratropiumbromide (atrovent®) on airways obstruction caused by edrophonium chloride (tensilon®). / Szathmáry, I.; Magyar, P.; Szobor, A.

In: European Neurology, Vol. 20, No. 1, 1981, p. 56-61.

Research output: Contribution to journalArticle

@article{132283958e6f4d9da6274d4af0344725,
title = "Myasthenia gravis: Protective effect of ipratropiumbromide (atrovent{\circledR}) on airways obstruction caused by edrophonium chloride (tensilon{\circledR})",
abstract = "The preventive effect of Atrovent{\circledR} Dosier-Aerosol on the airway flow resistance (Raw) caused by Tensilon{\circledR} was studied on 10 patients suffering from myasthenia gravis. Atrovent completely prevented the increase of Raw in 8 cases and considerably decreased it in 2 cases. The measure of the reaction observed may be influenced by the intensity of the cholinergic symptoms occurring on administration of Tensilon as well as by the magnitude of the initial Raw value. No side-effect which may be attributed to the administration of Atrovent could be observed, the substance did not increase the myasthenic symptoms. According to the study. Atrovent is a suitable medicine for the prevention of airway obstruction caused by Tensilon.",
keywords = "Airway obstruction, Edrophonium chloride, Ipratropium - bromide, Myasthenia gravis",
author = "I. Szathm{\'a}ry and P. Magyar and A. Szobor",
year = "1981",
doi = "10.1159/000115206",
language = "English",
volume = "20",
pages = "56--61",
journal = "European Neurology",
issn = "0014-3022",
publisher = "S. Karger AG",
number = "1",

}

TY - JOUR

T1 - Myasthenia gravis

T2 - Protective effect of ipratropiumbromide (atrovent®) on airways obstruction caused by edrophonium chloride (tensilon®)

AU - Szathmáry, I.

AU - Magyar, P.

AU - Szobor, A.

PY - 1981

Y1 - 1981

N2 - The preventive effect of Atrovent® Dosier-Aerosol on the airway flow resistance (Raw) caused by Tensilon® was studied on 10 patients suffering from myasthenia gravis. Atrovent completely prevented the increase of Raw in 8 cases and considerably decreased it in 2 cases. The measure of the reaction observed may be influenced by the intensity of the cholinergic symptoms occurring on administration of Tensilon as well as by the magnitude of the initial Raw value. No side-effect which may be attributed to the administration of Atrovent could be observed, the substance did not increase the myasthenic symptoms. According to the study. Atrovent is a suitable medicine for the prevention of airway obstruction caused by Tensilon.

AB - The preventive effect of Atrovent® Dosier-Aerosol on the airway flow resistance (Raw) caused by Tensilon® was studied on 10 patients suffering from myasthenia gravis. Atrovent completely prevented the increase of Raw in 8 cases and considerably decreased it in 2 cases. The measure of the reaction observed may be influenced by the intensity of the cholinergic symptoms occurring on administration of Tensilon as well as by the magnitude of the initial Raw value. No side-effect which may be attributed to the administration of Atrovent could be observed, the substance did not increase the myasthenic symptoms. According to the study. Atrovent is a suitable medicine for the prevention of airway obstruction caused by Tensilon.

KW - Airway obstruction

KW - Edrophonium chloride

KW - Ipratropium - bromide

KW - Myasthenia gravis

UR - http://www.scopus.com/inward/record.url?scp=0019379873&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019379873&partnerID=8YFLogxK

U2 - 10.1159/000115206

DO - 10.1159/000115206

M3 - Article

C2 - 6451430

AN - SCOPUS:0019379873

VL - 20

SP - 56

EP - 61

JO - European Neurology

JF - European Neurology

SN - 0014-3022

IS - 1

ER -