In the past 10 years, experience has been gained with combined VL-thalamotomy, pallidotomy and dentatomy using chronically implanted electrodes in Parkinson's disease. In the vast majority of cases, symptoms ceased surprisingly for 10-14 days just after stereotactic exploration of these motor centers. Clinical neurophysiological investigations (evoked responses, motor effects) show where consecutive lesions will be permanently effective at definitive coagulation. The physiological basis of these findings are discussed and a sophisticated therapeutic protocol is advised.
ASJC Scopus subject areas
- Clinical Neurology