Multiscale fractal analysis of cortical pyramidal neurons

Andreas Schierwagen, Luciano Da Fontoura Costa, Alan Alpár, Ulrich Gärtner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The present study used 3D data on neuronal morphology images to quantitatively characterize the phenotype of transgenic neurons. We calculated the multiscale fractal dimension (MFD) of reconstructed neuronal cells. It was shown that in a specific mouse mutant changes in the complexity of neuronal morphology correlate with changes in the MFD of dendrites of pyramidal neurons. Neurons in the mutant strain have lower peak fractal dimension compared with the wildtype, and a greater variety of the cell morphological phenotype.

Original languageEnglish
Title of host publicationBildverarbeitung fur die Medizin 2007
Subtitle of host publicationAlgorithmen - Systeme - Anwendungen, BVM 2007 - Proceedings des Workshops
Pages424-428
Number of pages5
Publication statusPublished - Dec 1 2007
EventWorkshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2007 - Workshop on Image Processing for Medicine: Algorithms - Systems - Applications, BVM 2007 - Munich, Germany
Duration: Mar 25 2007Mar 27 2007

Publication series

NameInformatik aktuell
ISSN (Print)1431-472X

Other

OtherWorkshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2007 - Workshop on Image Processing for Medicine: Algorithms - Systems - Applications, BVM 2007
CountryGermany
CityMunich
Period3/25/073/27/07

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ASJC Scopus subject areas

  • Modelling and Simulation

Cite this

Schierwagen, A., Da Fontoura Costa, L., Alpár, A., & Gärtner, U. (2007). Multiscale fractal analysis of cortical pyramidal neurons. In Bildverarbeitung fur die Medizin 2007: Algorithmen - Systeme - Anwendungen, BVM 2007 - Proceedings des Workshops (pp. 424-428). (Informatik aktuell).