Multifunctional role of pacap-like peptides in molluscs

T. Kiss, Z. Pirger

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The purpose of this review is to highlight the role of pituitary adenylate cyclase-activating polypeptide (PACAP) in a range of physiological and behavioral processes of gastropod molluscs, Helix and Lymnaea. Since its discovery in 1989 PACAP has become increasingly recognized for its important and diversified roles in the central and peripheral nervous system and in several peripheral organs of a variety of vertebrate and invertebrate species. Twenty-two years after its discovery, PACAP is now one of the most extensively studied of the neuropeptides. This review surveys the importance of PACAP and PACAP-like peptides in invertebrates, focusing mainly on the gastropod molluscs. The relevance of studies on lower vertebrates and invertebrates, which do not have a pituitary gland, is to contribute to the unraveling of fundamental effects of PACAP or PACAP-like peptides and to provide a comparative view.

Original languageEnglish
Pages (from-to)628-635
Number of pages8
JournalProtein and Peptide Letters
Volume20
Issue number6
DOIs
Publication statusPublished - Jun 2013

Fingerprint

Molluscs
Pituitary Adenylate Cyclase-Activating Polypeptide
Mollusca
Peptides
Invertebrates
Gastropoda
Vertebrates
Physiological Phenomena
Lymnaea
Peripheral Nervous System
Neurology
Pituitary Gland
Neuropeptides
Central Nervous System

Keywords

  • Antiapoptotic effect
  • Hibernation
  • Neuropeptide
  • PACAP

ASJC Scopus subject areas

  • Biochemistry
  • Structural Biology

Cite this

Multifunctional role of pacap-like peptides in molluscs. / Kiss, T.; Pirger, Z.

In: Protein and Peptide Letters, Vol. 20, No. 6, 06.2013, p. 628-635.

Research output: Contribution to journalArticle

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