Development of efficient screening methods has increasing significance in rapid evaluation of novel biocatalysts. Our study reveals the scopes and limitations of a novel GC-based multi-substrate screening method for initial characterization of the activity and selectivity of lipase biocatalysts. The multi-substrate kinetic resolution of four different racemic alcohols 1-4a by native and immobilized biocatalysts were analyzed by GC using enantiomer selective stationary phase.
|Number of pages||9|
|Journal||Studia Universitatis Babes-Bolyai Chemia|
|Publication status||Published - Dec 4 2012|
- Multi-substrate screening
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