Multi-substrate kinetic resolution screening method for lipase biocatalysts

Marton Osze, Diána Weiser, Gábor Hornyánszky, László Poppe

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1 Citation (Scopus)

Abstract

Development of efficient screening methods has increasing significance in rapid evaluation of novel biocatalysts. Our study reveals the scopes and limitations of a novel GC-based multi-substrate screening method for initial characterization of the activity and selectivity of lipase biocatalysts. The multi-substrate kinetic resolution of four different racemic alcohols 1-4a by native and immobilized biocatalysts were analyzed by GC using enantiomer selective stationary phase.

Original languageEnglish
Pages (from-to)129-137
Number of pages9
JournalStudia Universitatis Babes-Bolyai Chemia
Issue number2
Publication statusPublished - Dec 4 2012

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Keywords

  • Biocatalysis
  • Immobilization
  • Lipase
  • Multi-substrate screening

ASJC Scopus subject areas

  • Chemistry(all)

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