Mortalities associated with use of a commercial suspension of polyvinyl alcohol

I. Repa, G. P. Moradian, L. P. Dehner, S. M. Tadavarthy, D. W. Hunter, W. R. Castaneda-Zuniga, G. B. Wright, H. Katkov, P. Johnson, B. Chrenka, K. Amplatz

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40 Citations (Scopus)

Abstract

Two cases of symptomatic neonatal hepatic arteriovenous malformation (AVM) are presented. Both were treated with percutaneous transcatheter embolization and a commercially available polyvinyl alcohol suspension. Both infants died soon after AVM embolization. The results of laboratory examination of particle-size homogeneity of this commercial suspension demonstrate marked inhomogeneity of particle size very probably contributed to the death of these patients. A protocol has been developed to help determine appropriate particle size in individual cases; this may help prevent such catastrophic results during transcatheter embolization.

Original languageEnglish
Pages (from-to)395-399
Number of pages5
JournalRadiology
Volume170
Issue number2
DOIs
Publication statusPublished - Jan 1 1989

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Repa, I., Moradian, G. P., Dehner, L. P., Tadavarthy, S. M., Hunter, D. W., Castaneda-Zuniga, W. R., Wright, G. B., Katkov, H., Johnson, P., Chrenka, B., & Amplatz, K. (1989). Mortalities associated with use of a commercial suspension of polyvinyl alcohol. Radiology, 170(2), 395-399. https://doi.org/10.1148/radiology.170.2.2911663