Morphometric investigation of carotid body in sudden infant death syndrome.

Z. Pávai, Klára Töro, Eva Keller, János Jung

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND: The pathomechanism of sudden infant death syndrome (SIDS) has not been clarified yet. The high rate of early progenitor cells in carotid body has been reported as a pathognomic feature for SIDS. AIM AND STUDY DESIGN: The morphometric analysis was done by NIKON Eclipse microscope with a morphometric program Lucia G. SUBJECTS: This study was designed to investigate the structure and developmental state of carotid body in SIDS and non-SIDS cases. A comparison was made between the rates of dark and early progenitor cells. OUTCOME MEASURES: The Kruskal-Wallis test showed a significantly higher number of progenitor cells in the SIDS group than in controls (p=0.0003). RESULTS AND CONCLUSION: In this study on Hungarian SIDS cases we confirmed the observation that infants who died suddenly have an underdeveloped carotid body.

Original languageEnglish
Pages (from-to)93-97
Number of pages5
JournalRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Volume46
Issue number2
Publication statusPublished - 2005

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Embryology
  • Developmental Biology
  • Cell Biology

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