A light microscopic study of the thalamic ventro-basal complex (VB), after unilateral coagulation of vibrissa follicles in the newborn mouse, revealed an excess of neuronal perikarya on the contralateral 'deafferented' side as compared to the normal side. The higher density of nerve cells was confined to the vibrissal relay in the medial part of the VB nucleus (VB(m)), whereas the cell number in the non vibrissal-lateral part of this nucleus (VB1) remained at the control level. Electron microscopic investigation of the thalamic vibrissal relay has shown signs of a modified synaptogenesis on the 'deafferented' side: (a) the number of specific afferents diminished and in contrast to the normal side, most of the specific sensory terminals contain small spheroid synaptic vesicles and (b) the number of axon terminals with ovoid pleomorphic vesicles doubled.
|Number of pages||6|
|Journal||Comptes Rendus des Seances de l'Academie des Sciences - Series III|
|Publication status||Published - Aug 7 1985|
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Developmental Biology