Morphological, hemodynamic and stiffness changes in arteries of young smokers

Brigitta Léránt, Christina Straesser, Réka Katalin Kovács, L. Oláh, László Kardos, L. Csiba

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Aim: The aim of our investigations was to detect the acute and chronic effects of cigarette smoking on arterial wall thickness and stiffness in young, healthy volunteers. We also performed a one-year follow-up to define the possible changes. Subjects: We recruited 25 non-smoking and 25 smoking university students aged 19-33. Exclusion criteria were any known diseases, abnormally high cholesterol levels and body mass index (BMI) above 30 kg/m 2. Methods: We defined the intima-media thickness on both common carotid arteries by using Bmode ultrasonography and we measured the hemodynamic and stiffness parameters with the help of arteriograph. In case of smokers we also investigated the acute effects after smoking one cigarette. In the follow-up study we measured 15 non-smokers and 13 smokers again. Results: In the smoking group morphological, stiffness and hemodynamic parameters showed significantly higher values compared to non-smokers. Concerning the acute effects we detected a significant increase in stiffness and hemodynamic parameters after smoking one cigarette. Gender differences were also found in the smoking group. Unadjusted to age, gender and smoking status there was a significant correlation between intima-media thickness and pulse wave velocity. We could not find any progression in smokers after one year, while there was an improvement in intima-media thickness and augmentation index in non-smokers. Conclusion: Early atherosclerotic processes due to smoking can be detected even at a young age, in healthy university students. One year regular smoking does not result in detectable changes.

Original languageEnglish
Pages (from-to)152-155
Number of pages4
JournalPerspectives in Medicine
Volume1-12
DOIs
Publication statusPublished - Sep 2012

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Arteries
Hemodynamics
Smoking
Students
Pulse Wave Analysis
Common Carotid Artery
Hypercholesterolemia
Ultrasonography
Healthy Volunteers
Body Mass Index

Keywords

  • Intima-media thickness
  • Smoking
  • Stiffness

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Morphological, hemodynamic and stiffness changes in arteries of young smokers. / Léránt, Brigitta; Straesser, Christina; Kovács, Réka Katalin; Oláh, L.; Kardos, László; Csiba, L.

In: Perspectives in Medicine, Vol. 1-12, 09.2012, p. 152-155.

Research output: Contribution to journalArticle

Léránt, Brigitta ; Straesser, Christina ; Kovács, Réka Katalin ; Oláh, L. ; Kardos, László ; Csiba, L. / Morphological, hemodynamic and stiffness changes in arteries of young smokers. In: Perspectives in Medicine. 2012 ; Vol. 1-12. pp. 152-155.
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