Monte Carlo study of the selectivity of calcium channels: Improved geometrical model

D. Boda, Douglas Henderson, David D. Busath

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

An extended model of a calcium channel is described involving a channel with a finite length. With this new geometry the channel is still selective but less so than in an infinite cylinder geometry (Boda, D., Busath, D.D., Henderson, D., and Sokolowski, S., 2000, J. phys. Chem. B, 104, 8903). The selectivity of the channel depends on the width and length of the channel filter but is not significantly affected by changes in the size of the entry vestibules. Interestingly, changes in the size of the entry vestibules do affect the details of the concentration profiles of some of the ions.

Original languageEnglish
Pages (from-to)2361-2368
Number of pages8
JournalMolecular Physics
Volume100
Issue number14
DOIs
Publication statusPublished - Jul 20 2002

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Calcium Channels
calcium
selectivity
Ions
vestibules
Geometry
entry
geometry
filters
profiles
ions

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Monte Carlo study of the selectivity of calcium channels : Improved geometrical model. / Boda, D.; Henderson, Douglas; Busath, David D.

In: Molecular Physics, Vol. 100, No. 14, 20.07.2002, p. 2361-2368.

Research output: Contribution to journalArticle

Boda, D. ; Henderson, Douglas ; Busath, David D. / Monte Carlo study of the selectivity of calcium channels : Improved geometrical model. In: Molecular Physics. 2002 ; Vol. 100, No. 14. pp. 2361-2368.
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