Monocyte functions in patients with mixed connective tissue disease.

E. Bodolay, K. Lukács, G. Szabó, G. Frendl, T. Ben, G. Szegedi

Research output: Contribution to journalArticle

Abstract

The authors investigated the number and functions of peripheral blood monocytes in patients with mixed connective tissue disease. Moderate monocytopenia was detected in the active stage of the disease. There was a close correlation between the sensitized sheep red blood cell binding capacity of monocytes and the elevated levels of circulating immune complexes. The yeast phagocytosis of monocytes and the chemotactic activity were normal in patients with mixed connective tissue disease. C3b receptor mediated phagocytosis of monocytes decreased in the active and inactive stages of the disease. This study suggests that the decreased function of C3b receptors of monocytes is related to the pathogenesis of this disease.

Original languageEnglish
Pages (from-to)39-43
Number of pages5
JournalAllergologia et Immunopathologia
Volume17
Issue number1
Publication statusPublished - Jan 1989

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Mixed Connective Tissue Disease
Monocytes
Complement 3b Receptors
Phagocytosis
Antigen-Antibody Complex
Sheep
Yeasts
Erythrocytes

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Monocyte functions in patients with mixed connective tissue disease. / Bodolay, E.; Lukács, K.; Szabó, G.; Frendl, G.; Ben, T.; Szegedi, G.

In: Allergologia et Immunopathologia, Vol. 17, No. 1, 01.1989, p. 39-43.

Research output: Contribution to journalArticle

Bodolay, E. ; Lukács, K. ; Szabó, G. ; Frendl, G. ; Ben, T. ; Szegedi, G. / Monocyte functions in patients with mixed connective tissue disease. In: Allergologia et Immunopathologia. 1989 ; Vol. 17, No. 1. pp. 39-43.
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