Monocyte activation in patients with Hodgkin's disease

Maria Kávai, Ernö Berßnyi, Attila Zsindely, Gyula Szegedi, Läszlö Fésüs

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3 Citations (Scopus)


Transglutaminase activity in monocytes and serum lysozyme level were tested in 40 patients with Hodgkin's disease and were found to be significantly increased. Transglutaminase activity in monocytes from patients in a clinicaly active stage of the disease was higher than in clinically inactive cases of HD, and varied along with the histological subtypes. Serum lysozyme varied with the stage of the disease and with the symptomatology as well as with the histological subtype. The enzyme activities were higher before any treatment than after. A parallel increase of transglutaminase activity in monocytes and of serum lysozyme level suggests an elevated activity of the mononuclear phagocyte system in Hodgkin's disease.

Original languageEnglish
Pages (from-to)483-485
Number of pages3
JournalInternational Journal of Cancer
Issue number4
Publication statusPublished - Oct 1 1984


ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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