Monitoring the antioxidant activity of extracts originated from various Serratula species and isolation of flavonoids from Serratula coronata

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Abstract

The antioxidant effect of aqueous methanolic herb extracts of Serratula coronata, S. wolffii and S. tinctoria was investigated using both enzyme-dependent and enzyme-independent systems. The extracts displayed concentration-dependent inhibition of lipid peroxidation. Flavonoids and ecdysteroids present in the extracts were evaluated as antioxidant components. The flavonoid-containing fraction of the herb extract of S. coronata was more effective in lipid peroxidation than the ecdysteroid-containing fraction. This paper also reports the isolation of quercetin 3-O-methyl ether, apigenin, luteolin, quercetin, luteolin 4′β-D-glucoside and quercetin 4′β-D-glucoside from S. coronata.

Original languageEnglish
Pages (from-to)162-167
Number of pages6
JournalFitoterapia
Volume75
Issue number2
DOIs
Publication statusPublished - Mar 1 2004

Keywords

  • Antioxidant activity
  • Flavonoid
  • Serratula coronata
  • Serratula spp.

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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