Molecular structure and catechol oxidase activity of a new copper(I) complex with sterically crowded monodentate N-donor ligand

Ádám Kupán, J. Kaizer, G. Speier, Michel Giorgi, Marius Réglier, Ferenc Pollreisz

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

The attempted alkylation of 1,3-bis(2′-pyridylimino)isoindoline (indH) by the use of n-BuLi and subsequent alkyl halides led to quaternization of the pyridine nitrogens and the zwitterionic monodentate N-ligand (Me2ind)I was formed. By the use of the ligand the copper(I) complex [CuI (Me2 ind) I2] was prepared and its structure determined. It was found to be good catalyst for the oxidation of 3,5-di-tert-butylcatechol (DTBCH2) to 3,5-di-tert-butyl-1,2-benzoquinone (DTBQ) and H2O2 by dioxygen. Detailed kinetic studies revealed first-order dependence on the catalyst and dioxygen concentration and saturation type behavior with respect to the substrate.

Original languageEnglish
Pages (from-to)389-395
Number of pages7
JournalJournal of Inorganic Biochemistry
Volume103
Issue number3
DOIs
Publication statusPublished - Mar 2009

Fingerprint

Catechol Oxidase
Molecular Structure
Molecular structure
Copper
Oxygen
Ligands
Catalysts
Alkylation
Nitrogen
Oxidation
Kinetics
Substrates
n-butyllithium
pyridine
3,5-di-tert-butylcatechol
3,5-di-tert-butyl-1,2-benzoquinone

Keywords

  • Biomimetic oxidation
  • Catechol
  • Catechol oxidase
  • Copper complexes
  • N-ligand

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry

Cite this

Molecular structure and catechol oxidase activity of a new copper(I) complex with sterically crowded monodentate N-donor ligand. / Kupán, Ádám; Kaizer, J.; Speier, G.; Giorgi, Michel; Réglier, Marius; Pollreisz, Ferenc.

In: Journal of Inorganic Biochemistry, Vol. 103, No. 3, 03.2009, p. 389-395.

Research output: Contribution to journalArticle

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AU - Speier, G.

AU - Giorgi, Michel

AU - Réglier, Marius

AU - Pollreisz, Ferenc

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AB - The attempted alkylation of 1,3-bis(2′-pyridylimino)isoindoline (indH) by the use of n-BuLi and subsequent alkyl halides led to quaternization of the pyridine nitrogens and the zwitterionic monodentate N-ligand (Me2ind)I was formed. By the use of the ligand the copper(I) complex [CuI (Me2 ind) I2] was prepared and its structure determined. It was found to be good catalyst for the oxidation of 3,5-di-tert-butylcatechol (DTBCH2) to 3,5-di-tert-butyl-1,2-benzoquinone (DTBQ) and H2O2 by dioxygen. Detailed kinetic studies revealed first-order dependence on the catalyst and dioxygen concentration and saturation type behavior with respect to the substrate.

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