Molecular pathomechanisms of Alzheimer's disease

B. Penke, Z. Datki, C. Hetényi, Z. Molnár, I. Lengyel, K. Soós, M. Zarándi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

β-Amyloids are neurotoxic compounds produced in the brain and cause Alzheimer-type senile dementia. Their toxicity is in good correlation with their aggregation properties. Short peptide fragments of β-amyloid prevent Aβ-toxicity, probably by binding on the Aβ-aggregate surface.

Original languageEnglish
Pages (from-to)507-513
Number of pages7
JournalJournal of Molecular Structure: THEOCHEM
Volume666-667
DOIs
Publication statusPublished - Dec 29 2003

Fingerprint

Amyloid
toxicity
Toxicity
Alzheimer Disease
Peptide Fragments
Peptides
peptides
brain
Brain
Agglomeration
fragments
causes

Keywords

  • β-Amyloid
  • Alzheimer's disease
  • Neurodegeneration
  • Neuroprotection

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Computational Theory and Mathematics
  • Atomic and Molecular Physics, and Optics

Cite this

Molecular pathomechanisms of Alzheimer's disease. / Penke, B.; Datki, Z.; Hetényi, C.; Molnár, Z.; Lengyel, I.; Soós, K.; Zarándi, M.

In: Journal of Molecular Structure: THEOCHEM, Vol. 666-667, 29.12.2003, p. 507-513.

Research output: Contribution to journalArticle

Penke, B. ; Datki, Z. ; Hetényi, C. ; Molnár, Z. ; Lengyel, I. ; Soós, K. ; Zarándi, M. / Molecular pathomechanisms of Alzheimer's disease. In: Journal of Molecular Structure: THEOCHEM. 2003 ; Vol. 666-667. pp. 507-513.
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