A világossejtes veserák célzott terápiá ja és molekuláris patológiai alapjai

Translated title of the contribution: Molecular pathology and targeted therapy of clear cell renal cancer

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5 Citations (Scopus)

Abstract

The golden standard of care for advanced renal cell cancer (RCC) was until now the cytokine therapy with relatively low response rates. Advances of molecular genetics in RCC revealed several molecular targets such as VHL and angiogenic genotype or EGFR in the clear cell variant. Among the novel targeted agents, multiple tyrosine kinase inhibitors were proved to be clinically effective against advanced clear cell renal cancer, changing the standard of care. It is a further question how molecular diagnostics can improve these results by the detection of these targets or gene defects in individual tumors.

Original languageHungarian
Pages (from-to)309-314
Number of pages6
JournalMagyar onkologia
Volume50
Issue number4
Publication statusPublished - Dec 1 2006

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ASJC Scopus subject areas

  • Medicine(all)

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