The members of family Caliciviridae comprising many viruses are associated with a wide range of clinical syndromes in both humans and animals. Human caliciviruses (noroviruses, sapoviruses) are considered as human pathogenes, while animal caliciviruses (Lagovirus and Vesivirus genera) are known to be animal agents, however, zoonotic transmission of caliciviruses could not be excluded. For example, porcine enteric calicivirus (PEC), genetically described in 1999, is a swine virus, but it is a member of the "human" Sapovirus genus based on phylogenetic analysis. The etiologic role of noroviruses in gastroenteritis outbreaks in humans has been known in the country but there have not been reports on molecular detection of calicivirus in animals in Hungary. In March 2005, fecal samples from swine of gastroenteritis of unknown origin were collected on a pig farm in Somogy County, Hungary, and tested by reverse transcription-polymerase chain reaction (RT-PCR) followed by sequencing and phylogenetic analysis. Two of three samples collected from 10-12 days old domestic pigs were positive by RT-PCR and contained genetically identical PEC virus strains. Percentage of the nucleotide identity of the Hungarian PEC strains to the closest swine strain (swine/OH-JJ259/00/US), to the prototype PEC (PEC/Cowden) and to the human sapovirus detected in Hungary (HUNs11/2000/HUN) were 91%, 82% and 61%, respectively (Figure 2). Detection of porcine enteric calicivirus (PEC) indicates the possible presence and the possible etiological role of PEC in swine with gastroenteritis syndrome in Hungary.
|Translated title of the contribution||Molecular detection of porcine enteric calicivirus (PEC) in Hungary|
|Number of pages||6|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Dec 12 2006|
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