Molecular detection of novel adenoviruses in fecal specimens of captive monkeys with diarrhea in China

K. Bányai, M. D. Esona, A. Liu, Y. Wang, X. Tu, B. Jiang

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Adenovirus (AdV) has been recently detected among monkeys with diarrhea in a major research primate colony in China. To better assess disease burden and epidemiology of adenoviruses in the colony, we examined the prevalence of this virus in fecal specimens by PCR using broadly reactive hexon gene-specific primers. Of the 29 strains that were characterized by sequence and phylogenetic analysis, we identified a broad spectrum of simian AdV (SAdV) types, including species SAdV-A (n=14) and HAdV-G (n=9). Six additional strains represented two genetic clusters distantly related to other known SAdVs. A better understanding of the epidemiology of SAdVs and their potential role in gastroenteritis is critical to the implementation of advanced prevention strategies against AdV infection in captive primates.

Original languageEnglish
Pages (from-to)416-419
Number of pages4
JournalVeterinary Microbiology
Volume142
Issue number3-4
DOIs
Publication statusPublished - May 2010

Fingerprint

Adenoviridae
Primates
Haplorhini
monkeys
Diarrhea
diarrhea
China
Simian Adenoviruses
Epidemiology
Human adenovirus G
Adenoviridae Infections
epidemiology
Gastroenteritis
Sequence Analysis
burden of disease
gastroenteritis
Viruses
Polymerase Chain Reaction
sequence analysis
Research

Keywords

  • Diagnosis
  • Gastroenteritis
  • Simian adenovirus

ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

Cite this

Molecular detection of novel adenoviruses in fecal specimens of captive monkeys with diarrhea in China. / Bányai, K.; Esona, M. D.; Liu, A.; Wang, Y.; Tu, X.; Jiang, B.

In: Veterinary Microbiology, Vol. 142, No. 3-4, 05.2010, p. 416-419.

Research output: Contribution to journalArticle

Bányai, K. ; Esona, M. D. ; Liu, A. ; Wang, Y. ; Tu, X. ; Jiang, B. / Molecular detection of novel adenoviruses in fecal specimens of captive monkeys with diarrhea in China. In: Veterinary Microbiology. 2010 ; Vol. 142, No. 3-4. pp. 416-419.
@article{6c79fa9fff794bcd86f9aea693edba71,
title = "Molecular detection of novel adenoviruses in fecal specimens of captive monkeys with diarrhea in China",
abstract = "Adenovirus (AdV) has been recently detected among monkeys with diarrhea in a major research primate colony in China. To better assess disease burden and epidemiology of adenoviruses in the colony, we examined the prevalence of this virus in fecal specimens by PCR using broadly reactive hexon gene-specific primers. Of the 29 strains that were characterized by sequence and phylogenetic analysis, we identified a broad spectrum of simian AdV (SAdV) types, including species SAdV-A (n=14) and HAdV-G (n=9). Six additional strains represented two genetic clusters distantly related to other known SAdVs. A better understanding of the epidemiology of SAdVs and their potential role in gastroenteritis is critical to the implementation of advanced prevention strategies against AdV infection in captive primates.",
keywords = "Diagnosis, Gastroenteritis, Simian adenovirus",
author = "K. B{\'a}nyai and Esona, {M. D.} and A. Liu and Y. Wang and X. Tu and B. Jiang",
year = "2010",
month = "5",
doi = "10.1016/j.vetmic.2009.10.014",
language = "English",
volume = "142",
pages = "416--419",
journal = "Veterinary Microbiology",
issn = "0378-1135",
publisher = "Elsevier",
number = "3-4",

}

TY - JOUR

T1 - Molecular detection of novel adenoviruses in fecal specimens of captive monkeys with diarrhea in China

AU - Bányai, K.

AU - Esona, M. D.

AU - Liu, A.

AU - Wang, Y.

AU - Tu, X.

AU - Jiang, B.

PY - 2010/5

Y1 - 2010/5

N2 - Adenovirus (AdV) has been recently detected among monkeys with diarrhea in a major research primate colony in China. To better assess disease burden and epidemiology of adenoviruses in the colony, we examined the prevalence of this virus in fecal specimens by PCR using broadly reactive hexon gene-specific primers. Of the 29 strains that were characterized by sequence and phylogenetic analysis, we identified a broad spectrum of simian AdV (SAdV) types, including species SAdV-A (n=14) and HAdV-G (n=9). Six additional strains represented two genetic clusters distantly related to other known SAdVs. A better understanding of the epidemiology of SAdVs and their potential role in gastroenteritis is critical to the implementation of advanced prevention strategies against AdV infection in captive primates.

AB - Adenovirus (AdV) has been recently detected among monkeys with diarrhea in a major research primate colony in China. To better assess disease burden and epidemiology of adenoviruses in the colony, we examined the prevalence of this virus in fecal specimens by PCR using broadly reactive hexon gene-specific primers. Of the 29 strains that were characterized by sequence and phylogenetic analysis, we identified a broad spectrum of simian AdV (SAdV) types, including species SAdV-A (n=14) and HAdV-G (n=9). Six additional strains represented two genetic clusters distantly related to other known SAdVs. A better understanding of the epidemiology of SAdVs and their potential role in gastroenteritis is critical to the implementation of advanced prevention strategies against AdV infection in captive primates.

KW - Diagnosis

KW - Gastroenteritis

KW - Simian adenovirus

UR - http://www.scopus.com/inward/record.url?scp=77952425881&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952425881&partnerID=8YFLogxK

U2 - 10.1016/j.vetmic.2009.10.014

DO - 10.1016/j.vetmic.2009.10.014

M3 - Article

C2 - 19926233

AN - SCOPUS:77952425881

VL - 142

SP - 416

EP - 419

JO - Veterinary Microbiology

JF - Veterinary Microbiology

SN - 0378-1135

IS - 3-4

ER -