Molecular characterisation of invasive Streptococcus pyogenes isolates from Hungary obtained in 2004 and 2005

B. Krucsó, M. Gacs, B. Libisch, Zs Vargáné Hunyadi, K. Molnár, M. Füzi, J. Pászti

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11 Citations (Scopus)


Our aim was to characterise by molecular techniques group A streptococci isolated from invasive infections in Hungary in 2004-2005. Twenty-six nonduplicate invasive GAS isolates were selected and examined. The mortality rate proved high (52.3%) for those cases (n=21) where data were available. Predominant emm types were emm1 (n=13, 50%) and emm80 (n=5, 19.2%), but other M types (emm4, emm28, emm66, emm81.1, emm82, emm84) were also identified. Eight different PFGE types were distinguished, and each emm type showed an individual PFGE pattern. Our results show that-similarly to results obtained in several other countries-emm type 1 strains predominate among invasive GAS isolates, and that emm 1 type strains recovered from severe streptococcal infections were associated with the presence of the speA gene. The rate for macrolide resistance proved low: only two isolates showed elevated MICs for erythromycin.

Original languageEnglish
Pages (from-to)807-811
Number of pages5
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Issue number11
Publication statusPublished - Nov 1 2007


ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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