Molecular characterisation of invasive Streptococcus pyogenes isolates from Hungary obtained in 2004 and 2005

B. Krucsó, M. Gacs, B. Libisch, Zs Vargáné Hunyadi, K. Molnár, M. Füzi, J. Pászti

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Our aim was to characterise by molecular techniques group A streptococci isolated from invasive infections in Hungary in 2004-2005. Twenty-six nonduplicate invasive GAS isolates were selected and examined. The mortality rate proved high (52.3%) for those cases (n=21) where data were available. Predominant emm types were emm1 (n=13, 50%) and emm80 (n=5, 19.2%), but other M types (emm4, emm28, emm66, emm81.1, emm82, emm84) were also identified. Eight different PFGE types were distinguished, and each emm type showed an individual PFGE pattern. Our results show that-similarly to results obtained in several other countries-emm type 1 strains predominate among invasive GAS isolates, and that emm 1 type strains recovered from severe streptococcal infections were associated with the presence of the speA gene. The rate for macrolide resistance proved low: only two isolates showed elevated MICs for erythromycin.

Original languageEnglish
Pages (from-to)807-811
Number of pages5
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Volume26
Issue number11
DOIs
Publication statusPublished - Nov 2007

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Streptococcal Infections
Hungary
Streptococcus pyogenes
Macrolides
Erythromycin
Streptococcus
Mortality
Infection
Genes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Molecular characterisation of invasive Streptococcus pyogenes isolates from Hungary obtained in 2004 and 2005. / Krucsó, B.; Gacs, M.; Libisch, B.; Hunyadi, Zs Vargáné; Molnár, K.; Füzi, M.; Pászti, J.

In: European Journal of Clinical Microbiology and Infectious Diseases, Vol. 26, No. 11, 11.2007, p. 807-811.

Research output: Contribution to journalArticle

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AU - Pászti, J.

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