Molecular biology and role of histamine in physiological and pathological reactions. A review

I. Novák, A. Falus

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Histamine is known to exhibit a wide variety of both physiological and pathologic functions in different tissues and cells, this amine is one of the most general mediators of the mammalian organism. Extracellular histamine action is believed to be mediated by binding to its specific cell-surface receptor(s) resulting in the converting the extracellular signal to intracellular events. Moreover, numerous studies suggest basic role for intracellular histamine as one of the intracellular messenger moieties. The functional consequences of the action of histamine involve many physiological and pathophysiological events, including allergy, neurotransmission and cell growth.

Original languageEnglish
Pages (from-to)385-394
Number of pages10
JournalActa Biologica Hungarica
Volume48
Issue number4
Publication statusPublished - 1997

Fingerprint

allergy
Molecular biology
histamine
molecular biology
Histamine
Molecular Biology
Allergies
Cell Surface Receptors
Cell growth
amines
Synaptic Transmission
hypersensitivity
Amines
cell growth
Hypersensitivity
cells
Tissue
receptors
amine
organism

Keywords

  • Antihistamine
  • Biogenic amine
  • Histamine
  • Proliferation

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Molecular biology and role of histamine in physiological and pathological reactions. A review. / Novák, I.; Falus, A.

In: Acta Biologica Hungarica, Vol. 48, No. 4, 1997, p. 385-394.

Research output: Contribution to journalArticle

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