A hirtelen szívhalál molekuláris és genetikai háttere

Translated title of the contribution: Molecular and genetic background of sudden cardiac death

József Simkó, Z. Szabó, Kitti Barta, Dóra Újvárosi, P. Nánási, István Lorincz

Research output: Contribution to journalArticle

Abstract

Despite recent findings on the functional, structural and genetic background of sudden cardiac death, the incidence is still relatively high in the entire population. A thorough knowledge on susceptibility, as well as pathophysiology behind the development of malignant arrhythmias will help us to identify individuals at risk and prevent sudden cardiac death. This article presents a review of the current literature on the role of altered intracellular Ca2+ handling, acute myocardial ischaemia, cardiac autonomic innervation, renin-angiotensin-aldosterone system, monogenic and complex heritability in the pathogenesis of sudden cardiac death. Orv. Hetil., 2012, 153, 1967-1983.

Original languageHungarian
Pages (from-to)1967-1983
Number of pages17
JournalOrvosi Hetilap
Volume153
Issue number50
DOIs
Publication statusPublished - Dec 1 2012

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Sudden Cardiac Death
Molecular Biology
Renin-Angiotensin System
Myocardial Ischemia
Cardiac Arrhythmias
Incidence
Population
Genetic Background

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A hirtelen szívhalál molekuláris és genetikai háttere. / Simkó, József; Szabó, Z.; Barta, Kitti; Újvárosi, Dóra; Nánási, P.; Lorincz, István.

In: Orvosi Hetilap, Vol. 153, No. 50, 01.12.2012, p. 1967-1983.

Research output: Contribution to journalArticle

Simkó, J, Szabó, Z, Barta, K, Újvárosi, D, Nánási, P & Lorincz, I 2012, 'A hirtelen szívhalál molekuláris és genetikai háttere', Orvosi Hetilap, vol. 153, no. 50, pp. 1967-1983. https://doi.org/10.1556/OH.2012.29498
Simkó, József ; Szabó, Z. ; Barta, Kitti ; Újvárosi, Dóra ; Nánási, P. ; Lorincz, István. / A hirtelen szívhalál molekuláris és genetikai háttere. In: Orvosi Hetilap. 2012 ; Vol. 153, No. 50. pp. 1967-1983.
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