A hirtelen szívhalál molekuláris és genetikai háttere

Translated title of the contribution: Molecular and genetic background of sudden cardiac death

József Simkó, Zoltán Szabó, Kitti Barta, Dóra Újvárosi, Péter Nánási, István Lorincz

Research output: Contribution to journalArticle

Abstract

Despite recent findings on the functional, structural and genetic background of sudden cardiac death, the incidence is still relatively high in the entire population. A thorough knowledge on susceptibility, as well as pathophysiology behind the development of malignant arrhythmias will help us to identify individuals at risk and prevent sudden cardiac death. This article presents a review of the current literature on the role of altered intracellular Ca2+ handling, acute myocardial ischaemia, cardiac autonomic innervation, renin-angiotensin-aldosterone system, monogenic and complex heritability in the pathogenesis of sudden cardiac death. Orv. Hetil., 2012, 153, 1967-1983.

Translated title of the contributionMolecular and genetic background of sudden cardiac death
Original languageHungarian
Pages (from-to)1967-1983
Number of pages17
JournalOrvosi hetilap
Volume153
Issue number50
DOIs
Publication statusPublished - Dec 1 2012

ASJC Scopus subject areas

  • Medicine(all)

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