Modifying the physicochemical properties of NSAIDs for nasal and pulmonary administration

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This review focuses on nasal and pulmonary delivery of NSAIDs (non-steroidal anti-inflammatory drugs) for fast-onset analgesia, for the potential prevention of Alzheimer's disease (AD), as well as for an add-on treatment in cystic fibrosis (CF) and non-small cell lung cancer (NSCLC). I discuss how the physicochemical properties of NSAIDs can be modified with respect to the biological characteristics of the target site. Innovative technology and/or dosage forms can promote an effective therapy.

Original languageEnglish
JournalDrug Discovery Today: Technologies
DOIs
Publication statusAccepted/In press - Jan 1 2018

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Intranasal Administration
Anti-Inflammatory Agents
Lung
Dosage Forms
Nose
Cystic Fibrosis
Non-Small Cell Lung Carcinoma
Pharmaceutical Preparations
Analgesia
Alzheimer Disease
Technology
Therapeutics

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Medicine
  • Drug Discovery

Cite this

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