Modelling thrombopoiesis regulation-I. Model description and stimulation results

J. Eller, I. Györi, M. Zöllei, F. Krizsa

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Abstract

This paper gives a detailed account of the authors' mathematical model of thrombopoiesis regulation. A special feature of the model is the consequent use of Von Foerster's partial differential equation for the description of age-structured compartments, where regulation effects are built into the Von Foerster growth coefficient. For the computer solution of the model equations-which include ordinary as well as partial differential equations-the authors developed an approximation scheme. Results of computer simulation of the model are also presented.

Original languageEnglish
Pages (from-to)841-848
Number of pages8
JournalComputers and Mathematics with Applications
Volume14
Issue number9-12
DOIs
Publication statusPublished - 1987

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ASJC Scopus subject areas

  • Modelling and Simulation
  • Computational Theory and Mathematics
  • Computational Mathematics

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