Model of a thalamocortical neurone with dendritic voltage-gated ion channels

Károly Antal, Zsuzsa Emri, Tibor I. Tóth, Vincenzo Crunelli

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

To investigate the functional role of dendrites of thalamocortical neurones, we have used our one-compartmental model to construct a multi-compartmental model with dendritic regions chosen according to a representative soma-to-dendritic terminal path of an X cell of the cat dorsal lateral geniculate nucleus. The multi-compartmental model with dendritic low-threshold Ca2+ and delayed rectifier K+ channels yields more accurate results than the one-compartmental model when simulating tonic firing and oscillatory activities, and provides a useful means for the study of propagation of excitation on the dendrites.

Original languageEnglish
Pages (from-to)2655-2658
Number of pages4
JournalNeuroreport
Volume7
Issue number15-17
DOIs
Publication statusPublished - Jan 1 1996

Keywords

  • Cable equation
  • Dendritic Ca channels
  • Multi-compartmental model
  • T-type Ca current
  • Thalamic oscillations
  • dLGN neurones

ASJC Scopus subject areas

  • Neuroscience(all)

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