Model-based planning of short-term insulin therapy

T. Deutsch, I. Futo, G. Tamás

Research output: Contribution to journalArticle

Abstract

Drugs are administered to achieve a therapeutic objective. They can only be practically affected by controlling the manner in which they enter the body. In the open-loop control of drug response, optimization is based on calculations made by use of the pretreatment clinical parameters of the individual patent while in the closed-loop control of drug effect the observed characteristics and intensity of drug response are used to modify drug input according to the momentary need of the patient during therapy. Since the intensity and time patterns of the drug-elicited response are determined by the individual characteristics of the drug input-pharmacological response output relationship of the patient, mathematical models that describe this relationship can help to guide clinical therapy in a more rational way.

Original languageEnglish
Pages (from-to)267-271
Number of pages5
JournalMeasurement and Control
Volume23
Issue number9
Publication statusPublished - Nov 1990

Fingerprint

insulin
Insulin
Therapy
planning
therapy
Drugs
drugs
Planning
Model-based
Mathematical models
Open-loop Control
patents
Patents
Closed-loop Control
pretreatment
mathematical models
Mathematical Model
optimization
Optimization
output

ASJC Scopus subject areas

  • Instrumentation

Cite this

Model-based planning of short-term insulin therapy. / Deutsch, T.; Futo, I.; Tamás, G.

In: Measurement and Control, Vol. 23, No. 9, 11.1990, p. 267-271.

Research output: Contribution to journalArticle

Deutsch, T, Futo, I & Tamás, G 1990, 'Model-based planning of short-term insulin therapy', Measurement and Control, vol. 23, no. 9, pp. 267-271.
Deutsch, T. ; Futo, I. ; Tamás, G. / Model-based planning of short-term insulin therapy. In: Measurement and Control. 1990 ; Vol. 23, No. 9. pp. 267-271.
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