Mixed meningeal and brain plasma-cell granuloma: An example of an unusual evolution

Pierre Hughes Roche, D. Figarella-Branger, W. Pellet, F. Isamat, A. Buki

Research output: Contribution to journalArticle

10 Citations (Scopus)


We report a study of a 22-year-old woman with a plasma-cell granuloma (PCG), a rare intracranial lesion characterized by a non-neoplastic polyclonal proliferation of plasma cells and other mononuclear cells. She presented after a generalized seizure and CT-scan and magnetic resonance images demonstrated a left temporo-basal tumour mass involving both the meningeal layers and the brain parenchyma. Histopathological examination of a biopsy led to the diagnosis of a typical PCG. After a short course of steroid administration, the clinical and radiological features improved and complete regression of the lesion was shown after one year and persisted at four-year follow-up. This dramatic regression of an intracranial PCG shows that neither surgical removal nor radiation therapy is required to treat a broad skull base PCG.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalActa neurochirurgica
Issue number1
Publication statusPublished - Jan 1 2004



  • Brain pathology
  • Inflammatory pseudotumour
  • Plasmacell granuloma
  • Polyclonal plasma cell proliferation

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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