Mixed germ cell tumour of the central nervous system with multiple metastases - A 5-year history. A case report

J. Áfra, I. Jelencsik, F. Gyergyai, F. Slowik, J. Kenéz

Research output: Contribution to journalArticle

Abstract

After a 4-month history of intermittent headache an intrasellar benign teratoma was found and totally removed in a 19-year-old male patient who became symptom-free. Three years later a third ventricle germinoma developed which was also totally removed, followed by local radiotherapy. Eight months later a spinal tumour evolved, chemotherapy and radiotherapy resulted in full recovery. Eighteen months later a frontal meningeal tumour appeared and was treated by chemotherapy. Three months later - with chemotherapy - tumorous meningitis developed and the patient died 5 years after the first operation. The results of tumour-markers monitoring, histology, electronmicroscopy and immunohistochemistry referred to a germinoma with multiple metastases and meningeal seeding after total removal of an intrasellar mature teratoma.

Original languageEnglish
Pages (from-to)78-82
Number of pages5
JournalEuropean Journal of Neurology
Volume3
Issue number1
Publication statusPublished - 1996

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Nervous System Neoplasms
Germ Cell and Embryonal Neoplasms
Germinoma
Central Nervous System
History
Teratoma
Neoplasm Metastasis
Drug Therapy
Meningeal Neoplasms
Radiotherapy
Third Ventricle
Tumor Biomarkers
Meningitis
Headache
Histology
Immunohistochemistry
Neoplasms

Keywords

  • chemotherapy
  • germinoma
  • metastasis
  • radiotherapy
  • teratoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Mixed germ cell tumour of the central nervous system with multiple metastases - A 5-year history. A case report. / Áfra, J.; Jelencsik, I.; Gyergyai, F.; Slowik, F.; Kenéz, J.

In: European Journal of Neurology, Vol. 3, No. 1, 1996, p. 78-82.

Research output: Contribution to journalArticle

Áfra, J. ; Jelencsik, I. ; Gyergyai, F. ; Slowik, F. ; Kenéz, J. / Mixed germ cell tumour of the central nervous system with multiple metastases - A 5-year history. A case report. In: European Journal of Neurology. 1996 ; Vol. 3, No. 1. pp. 78-82.
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