Mixed acetals of cyclodextrins. Preparation of hexakis-, heptakis- and octakis[2,6-di-O-(methoxydimethyl)methyl]-α-, β- and γ-cyclodextrins

András Lipták, Lóránt Jánossy, Anikó Borbás, József Szejtli

Research output: Contribution to journalArticle

9 Citations (Scopus)


The proton-catalyzed addition of 2-methoxypropene to α-, β- and γ-cyclodextrins resulted in hexakis-, heptakis-, and octakis[2,6-di-O-(methoxydimethyl)methyl]-α-, β- and γ-cyclodextrins, but no reaction was observed of CD-s with 2,2-dimethoxypropane. The mixed acetal-type compounds can be alkylated under basic conditions. The preparation of hexakis(3-O-benzyl)-α-cyclodextrin demonstrates the synthetic value of this methodology.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalCarbohydrate Research
Issue number2
Publication statusPublished - Jan 1 2002



  • (Methoxydimethyl)methyl ethers
  • 3-O-Benzyl-α-CD
  • Mixed acetals of cyclodextrin
  • Proton-catalyzed addition of 2-methoxypropene

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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