Mitochondrial D-loop analysis reveals low diversity in Mangalica pigs and their relationship to historical specimens

J. Molnár, G. Tóth, V. Stéger, A. Zsolnai, A. Jánosi, A. Mohr, R. Szántó-Egész, P. Tóth, A. Micsinai, J. Rátky, F. Marincs

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The genetic relationship between 195 Mangalica and 79 non-Mangalica pigs was studied using mitochondrial D-loop SNP genotyping. Altogether, 35 polymorphic sites and 27 haplotypes were identified. Of the haplotypes, eight and 16 are Mangalica and non-Mangalica specific, respectively, while three contain both Mangalica and non-Mangalica individuals. Genetic distance values and phylogenetic analysis indicate that Mangalica individuals are very closely related, and five haplotypes represent approximately 92% of the Mangalica pigs involved in the study, thus determining the major maternal lineages. In contrast to previous microsatellite studies, individuals of Mangalica could not be distinguished as three separate breeds using mtDNA genotyping. Comparing modern and archaeological mtDNA sequences revealed that present day Mangalica is related to pigs that lived in the Carpathian basin where postulated ancestors of Mangalica also lived. This is the first DNA-based genetic evidence to support the described breeding history of Mangalica.

Original languageEnglish
Pages (from-to)312-320
Number of pages9
JournalJournal of Animal Breeding and Genetics
Volume130
Issue number4
DOIs
Publication statusPublished - Aug 2013

Fingerprint

Haplotypes
haplotypes
Swine
Mitochondrial DNA
genotyping
swine
mitochondrial DNA
maternal lineage
Microsatellite Repeats
genetic relationships
Breeding
genetic distance
Single Nucleotide Polymorphism
ancestry
Mothers
microsatellite repeats
basins
breeds
DNA
phylogeny

Keywords

  • Ancestor DNA
  • Genetic distances
  • Phylogenetic tree
  • Pig breeds
  • SNP

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Food Animals
  • Medicine(all)

Cite this

Mitochondrial D-loop analysis reveals low diversity in Mangalica pigs and their relationship to historical specimens. / Molnár, J.; Tóth, G.; Stéger, V.; Zsolnai, A.; Jánosi, A.; Mohr, A.; Szántó-Egész, R.; Tóth, P.; Micsinai, A.; Rátky, J.; Marincs, F.

In: Journal of Animal Breeding and Genetics, Vol. 130, No. 4, 08.2013, p. 312-320.

Research output: Contribution to journalArticle

Molnár, J, Tóth, G, Stéger, V, Zsolnai, A, Jánosi, A, Mohr, A, Szántó-Egész, R, Tóth, P, Micsinai, A, Rátky, J & Marincs, F 2013, 'Mitochondrial D-loop analysis reveals low diversity in Mangalica pigs and their relationship to historical specimens', Journal of Animal Breeding and Genetics, vol. 130, no. 4, pp. 312-320. https://doi.org/10.1111/j.1439-0388.2012.01014.x
Molnár, J. ; Tóth, G. ; Stéger, V. ; Zsolnai, A. ; Jánosi, A. ; Mohr, A. ; Szántó-Egész, R. ; Tóth, P. ; Micsinai, A. ; Rátky, J. ; Marincs, F. / Mitochondrial D-loop analysis reveals low diversity in Mangalica pigs and their relationship to historical specimens. In: Journal of Animal Breeding and Genetics. 2013 ; Vol. 130, No. 4. pp. 312-320.
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