Mimicking catalase and catecholase enzymes by copper(II)-containing complexes

István Szilágyi, László Horváth, Imre Labádi, Klara Hernadi, István Pálinkó, Tamás Kiss

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

An imidazolate-bridged copper(II)-zinc(II) complex (Cu(II)-diethylenetriamino-μ-imidazolato-Zn(II)-tris(2-aminoethyl) amine perchlorate (denoted as "Cu,Zn complex") and a simple copper(II) complex (Cu(II)-tris(2-aminoethyl) amine chloride ("Cu-tren") were prepared and immobilised on silica gel (by hydrogen or covalent bonds) and montmorillonite (by ion exchange). The immobilised substances were characterised by FT-IR spectroscopy and their thermal characteristics were also studied. The obtained materials were tested in two probe reactions: Catalytic oxidation of 3,5-di-tert-butyl catechol (DTBC) (catecholase activity) and the decomposition of hydrogen peroxide (catalase activity). It was found that the catecholase activity of the Cu,Zn complex increased considerably upon immobilization on silica gel via hydrogen bonds and intercalation by ion exchange among the layers of montmorillonite. The imidazolate-bridged copper(II)-zinc(II) complex and its immobilised versions were inactive in hydrogen peroxide decomposition. The Cu(II)-tris(2-aminoethyl)amine chloride complex displayed good catalase activity; however, immobilisation could not improve it.

Original languageEnglish
Pages (from-to)118-134
Number of pages17
JournalCentral European Journal of Chemistry
Volume4
Issue number1
DOIs
Publication statusPublished - Mar 1 2006

Keywords

  • Catalase activity
  • Catecholase activity
  • Copper(II) complexes
  • Enzyme mimics
  • Immobilisation

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

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