Migration rates and genetic structure of two Hungarian ethnic groups in Transylvania, Romania

A. Brandstätter, B. Egyed, B. Zimmermann, N. Duftner, Z. Padar, Walther Parson

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Transylvania's ethnic mosaic is composed of Romanians, German Saxons and Hungarians. The ethnic groups of the Hungarian minority that settled in Romania show differences in dialects, customs and religious affiliations. In this study entire mtDNA control region sequences from 360 individuals of Hungarian ethnicity from two populations (the Csángóand the Székely), settled in the historical region of Transylvania in Romania, were generated and analyzed following high quality sequencing standards. Phylogenetic analyses were used for haplogroup determination, quasi-median network analyses were applied for the visualization of character conflicts, and median joining reconstructions were used for depicting haplotype structures. Affiliation of haplotypes to major west Eurasian haplogroups was confirmed using coding region SNPs. Gene flow between the two populations was low and biased towards a higher migration rate from the Csángóto the Székely than vice versa. Phylogeographic analyses revealed effects of genetic isolation within the Csángópopulation, which is, in its genetic structure, clearly different from the Székely population. The pronounced genetic divergence between the two populations is in sharp contrast to the expectation of high genetic similarity due to the close geographic proximity of their native homelands. The population data will be incorporated in the EMPOP database (http://www.empop.org).

Original languageEnglish
Pages (from-to)791-803
Number of pages13
JournalAnnals of Human Genetics
Volume71
Issue number6
DOIs
Publication statusPublished - Nov 2007

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Romania
Genetic Structures
Ethnic Groups
Population
Haplotypes
Gene Flow
Mitochondrial DNA
Single Nucleotide Polymorphism
Databases

Keywords

  • AMOVA
  • East European populations
  • Haplogroup assignment
  • Migration rates
  • Network analyses
  • Phylogeographic analyses

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Migration rates and genetic structure of two Hungarian ethnic groups in Transylvania, Romania. / Brandstätter, A.; Egyed, B.; Zimmermann, B.; Duftner, N.; Padar, Z.; Parson, Walther.

In: Annals of Human Genetics, Vol. 71, No. 6, 11.2007, p. 791-803.

Research output: Contribution to journalArticle

Brandstätter, A. ; Egyed, B. ; Zimmermann, B. ; Duftner, N. ; Padar, Z. ; Parson, Walther. / Migration rates and genetic structure of two Hungarian ethnic groups in Transylvania, Romania. In: Annals of Human Genetics. 2007 ; Vol. 71, No. 6. pp. 791-803.
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