Microwave-assisted amidation of arylacetic acids by reaction with 2-aryl-ethylamines

Alajos Grün, Mátyás Milen, Tamás Földesi, Péter Ábrányi-Balogh, László Drahos, György Keglevich

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Twenty-five amides were synthesized in almost quantitative yields by microwaveassisted condensation of arylacetic acids and 2-aryl-ethylamines under solventless conditions. The N-arylethyl-arylacetylamides are intermediates of the corresponding isoquinoline derivates. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications1 to view the free supplemental file.

Original languageEnglish
Pages (from-to)1491-1498
Number of pages8
JournalSynthetic Communications
Volume43
Issue number11
DOIs
Publication statusPublished - Apr 22 2013

Keywords

  • Amidation
  • Arylacetic acid
  • Arylethylamine
  • Microwave
  • Solventless

ASJC Scopus subject areas

  • Organic Chemistry

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