Microscopic colitis: A retrospective study of clinical presentation in 53 patients

Zsolt Barta, Gabriella Mekkel, István Csípo, László Tóth, Szabolcs Szakáll, Gábor G. Szabó, Gyula Bakó, Gyula Szegedi, Margit Zeher

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32 Citations (Scopus)


Aim: To evaluate the relationship between symptoms and microscopic colitis (MC) subtypes: to test whether collagenous colitis (CC) and/or lymphocytic colitis (LC) might be related to both constipation and diarrhea. Methods: A cohort of patients with independently confirmed typical histopathological changes was investigated. Fifty-three patients with histologically proved MC (46 with CC, 7 with LC) were included. The existence of diarrhea or constipation and the co-existence of autoimmune diseases were also investigated and all data were retrospectively analyzed. Results: Twenty-three (43.39%) of MC patients had chronic constipation (20 in CC, 3 in LC patients). Twenty-four (45.28%) of MC patients had autoimmune disease and the diagnosis of autoimmune disease was always prior to MC. Sjögren's syndrome was associated only with the constipation subgroup. Conclusion: The Janus face of MC resembles the subgroups of irritable bowel syndrome. The co-existence of autoimmune diseases and MC is confirmed in both the constipation and diarrhea subgroups.

Original languageEnglish
Pages (from-to)1351-1355
Number of pages5
JournalWorld journal of gastroenterology
Issue number9
Publication statusPublished - Mar 7 2005


  • Autoimmune
  • Constipation
  • Microscopic colitis

ASJC Scopus subject areas

  • Gastroenterology

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