Microlissencephaly

L. Sztriha, Lihadh Al-Gazali, Erzsébet Várady, Michael Nork, Mani Varughese

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

An inbred Arab family with three neonates affected by microlissencephaly syndrome is reported. Brain magnetic resonance imaging in the index case revealed very thin brain mantle with agyria-pachygyria, agenesis of the corpus callosum, and hypoplasia of the brainstem and cerebellum. All three neonates had microcephaly, arthrogryposis multiplex congenita, and micropenis. The presence of three affected newborn infants in a consanguineous family suggests an autosomal-recessive mode of inheritance of this syndrome. The spectrum of microlissencephaly syndrome is reviewed.

Original languageEnglish
Pages (from-to)362-365
Number of pages4
JournalPediatric Neurology
Volume18
Issue number4
DOIs
Publication statusPublished - Apr 1998

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Microcephaly
Lissencephaly
Newborn Infant
Arthrogryposis
Agenesis of Corpus Callosum
Brain
Cerebellum
Brain Stem
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Sztriha, L., Al-Gazali, L., Várady, E., Nork, M., & Varughese, M. (1998). Microlissencephaly. Pediatric Neurology, 18(4), 362-365. https://doi.org/10.1016/S0887-8994(97)00213-0

Microlissencephaly. / Sztriha, L.; Al-Gazali, Lihadh; Várady, Erzsébet; Nork, Michael; Varughese, Mani.

In: Pediatric Neurology, Vol. 18, No. 4, 04.1998, p. 362-365.

Research output: Contribution to journalArticle

Sztriha, L, Al-Gazali, L, Várady, E, Nork, M & Varughese, M 1998, 'Microlissencephaly', Pediatric Neurology, vol. 18, no. 4, pp. 362-365. https://doi.org/10.1016/S0887-8994(97)00213-0
Sztriha L, Al-Gazali L, Várady E, Nork M, Varughese M. Microlissencephaly. Pediatric Neurology. 1998 Apr;18(4):362-365. https://doi.org/10.1016/S0887-8994(97)00213-0
Sztriha, L. ; Al-Gazali, Lihadh ; Várady, Erzsébet ; Nork, Michael ; Varughese, Mani. / Microlissencephaly. In: Pediatric Neurology. 1998 ; Vol. 18, No. 4. pp. 362-365.
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