Microlissencephaly

László Sztriha, Lihadh Al-Gazali, Erzsébet Várady, Michael Nork, Mani Varughese

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23 Citations (Scopus)

Abstract

An inbred Arab family with three neonates affected by microlissencephaly syndrome is reported. Brain magnetic resonance imaging in the index case revealed very thin brain mantle with agyria-pachygyria, agenesis of the corpus callosum, and hypoplasia of the brainstem and cerebellum. All three neonates had microcephaly, arthrogryposis multiplex congenita, and micropenis. The presence of three affected newborn infants in a consanguineous family suggests an autosomal-recessive mode of inheritance of this syndrome. The spectrum of microlissencephaly syndrome is reviewed.

Original languageEnglish
Pages (from-to)362-365
Number of pages4
JournalPediatric Neurology
Volume18
Issue number4
DOIs
Publication statusPublished - Apr 1 1998

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Sztriha, L., Al-Gazali, L., Várady, E., Nork, M., & Varughese, M. (1998). Microlissencephaly. Pediatric Neurology, 18(4), 362-365. https://doi.org/10.1016/S0887-8994(97)00213-0