Microbiological profile of adenoid hypertrophy correlates to clinical diagnosis in children

Anita Szalmás, Z. Papp, Péter Csomor, József Kónya, I. Sziklai, Z. Szekanecz, T. Karosi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective. Adenoid hypertrophy is a common condition in childhood, which may be associated with recurring acute otitis media (RAOM), otitis media with effusion (OME), and obstructive sleep apnea syndrome (OSAS). These different clinical characteristics have some clinical overlap; however, they might be explained by distinct immunologic and infectious profiles and result in various histopathologic findings of adenoid specimens. Methods. A total of 59 children with adenoid hypertrophy undergoing adenoidectomy were studied. Three series of identical adenoid specimens were processed to hematoxylin-eosin (H.E.) and Gram staining and to respiratory virus specific real-time PCR, respectively. Results. According to the clinical characteristics, patients were recruited into three groups: RAOM (n=25), OME (n=19), and OSAS (n=15). Bacterial biofilms were detected in 21 cases, while at least one of the studied respiratory viruses was detected in 52 specimens. RAOM cases were significantly associated with biofilm existence (n=20, P

Original languageEnglish
Article number629607
JournalBioMed Research International
Volume2013
DOIs
Publication statusPublished - 2013

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Adenoids
Biofilms
Viruses
Hypertrophy
Otitis Media
Otitis Media with Effusion
Obstructive Sleep Apnea
Hematoxylin
Eosine Yellowish-(YS)
Adenoidectomy
Real-Time Polymerase Chain Reaction
Staining and Labeling
Sleep

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Microbiological profile of adenoid hypertrophy correlates to clinical diagnosis in children. / Szalmás, Anita; Papp, Z.; Csomor, Péter; Kónya, József; Sziklai, I.; Szekanecz, Z.; Karosi, T.

In: BioMed Research International, Vol. 2013, 629607, 2013.

Research output: Contribution to journalArticle

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AU - Csomor, Péter

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AU - Szekanecz, Z.

AU - Karosi, T.

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