Mg-Al 3: 1 Hydrotalcite catalyst in the synthesis of cyclopropane carboxylic acid derivatives

Zoltán Finta, Z. Hell, Daniella Balán, Agnieszka Cwik, S. Kemény, François Figueras

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The non-activated Mg-Al 3:1 hydrotalcite is a suitable basic catalyst both in the intramolecular cyclization reaction of malonic acid allylic esters into bicyclic cyclopropane carboxylic acid lactones and the intermolecular cyclization reaction of dibromoethane and diethyl malonate into cyclopropane dicarboxylic acid diester. The optimal reaction conditions of the intramolecular cyclization were determined using a 24 factorial design. An interesting effect on the diastereoselectivity of the intramolecular cyclization was observed compared with the diastereoselectivity of this cyclization using solid potassium carbonate as base. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)149-155
Number of pages7
JournalJournal of Molecular Catalysis A: Chemical
Volume161
Issue number1-2
DOIs
Publication statusPublished - Nov 6 2000

Fingerprint

hydrotalcite
cyclopropane
Cyclization
Carboxylic acids
carboxylic acids
Derivatives
catalysts
Catalysts
synthesis
factorial design
dicarboxylic acids
esters
carbonates
potassium
Dicarboxylic Acids
Potash
Acids
Lactones
acids
Esters

Keywords

  • Cyclopropane carboxylic acid derivatives
  • Hydrotalcite catalyst
  • Intramolecular cyclization reaction

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology

Cite this

Mg-Al 3 : 1 Hydrotalcite catalyst in the synthesis of cyclopropane carboxylic acid derivatives. / Finta, Zoltán; Hell, Z.; Balán, Daniella; Cwik, Agnieszka; Kemény, S.; Figueras, François.

In: Journal of Molecular Catalysis A: Chemical, Vol. 161, No. 1-2, 06.11.2000, p. 149-155.

Research output: Contribution to journalArticle

Finta, Zoltán ; Hell, Z. ; Balán, Daniella ; Cwik, Agnieszka ; Kemény, S. ; Figueras, François. / Mg-Al 3 : 1 Hydrotalcite catalyst in the synthesis of cyclopropane carboxylic acid derivatives. In: Journal of Molecular Catalysis A: Chemical. 2000 ; Vol. 161, No. 1-2. pp. 149-155.
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