Methylglyoxal and cell viability

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

1. 1. Methylglyoxal by depleting glutathione stores increased Trypan-blue uptake by the cells incubated in glucose, pyruvate and amino acids free medium. 2. 2. Only a transient fall of glutathione concentration without any effect on cell viability was caused by methylglyoxal when the medium was supplemented with above-mentioned compounds. 3. 3. The role of gamma-glutamyl-transpeptidase is discussed.

Original languageEnglish
Pages (from-to)987-990
Number of pages4
JournalInternational Journal of Biochemistry
Volume26
Issue number8
DOIs
Publication statusPublished - 1994

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Pyruvaldehyde
Glutathione
Cell Survival
Cells
Trypan Blue
gamma-Glutamyltransferase
Pyruvic Acid
Amino Acids
Glucose

ASJC Scopus subject areas

  • Biochemistry

Cite this

Methylglyoxal and cell viability. / Braun, L.; Garzó, Tamás; Riba, P.; Mandl, J.; Kalapos, M.

In: International Journal of Biochemistry, Vol. 26, No. 8, 1994, p. 987-990.

Research output: Contribution to journalArticle

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