Methodological problems of the radioimmunological glucagon determination

L. Koranyi, F. Peterfy, Z. Tulassay

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Glucagon radioimmunoassay establishment with antiglucagon rabbit serum, and its difficulties are reported. Attention must be paid to the importance in the laboratory of glucagon-binding antibodies in the blood of insulin-treated diabetics. These antibodies bind the circulating endogenous glucagon, as well as 125I-glucagon. Thus their removal from the sample becomes necessary. As an example of clinical use of glucagon radioimmunoassay, the glucagon level of patients after pancreatography, that of polytraumatized and cranially injured patients is reviewed.

Original languageEnglish
Pages (from-to)43-54
Number of pages12
JournalDiabetologia Croatica
Volume6
Issue number1
Publication statusPublished - Jan 1 1977

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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