A Staphylococcusok methicillinrezisztenciája és a kimutatásukra szolgáló módszer.

Translated title of the contribution: Methicillin-resistance of staphylococci and methods of detection

Tóth Mónika Fehérváriné, F. Rozgonyi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In Hungary more than 25% of Staphylococcus aureus strains and 33.4-70.1% of strains of different coagulase-negative Staphylococcus species isolated from inpatients in the last five years were methicillin-resistant. These are great clinical problems because the methicillin-resistant strains are resistant to all beta-lactam antibiotics, furthermore, most of them exhibit multiple resistance, too. For these reasons, the fast and exact microbiological diagnosis is of utmost basic and life-saving importance. In this review the most important evidences for proving pathogenicity and virulence of methicillin-resistant S. aureus strains and our knowledge on the origin, genetic background, conditions of expression, forms of appearance, phenotypical and genotypical properties of methicillin resistance are summarised. Phenotypical semiquantitative and quantitative methods aiming the detection of methicillin resistance are shown with their advantages and restrictions. Genetic methods applicable to detect mecA gene responsible for coding methicillin resistance, furthermore, those by which clonal and genomic relationship and spread can be proven in epidemic cases are presented. Finally, up-to-date schemes for a proper identification as well as systemic and local elimination of methicillin resistant Staphylococcus strains are suggested.

Original languageHungarian
Pages (from-to)107-115
Number of pages9
JournalOrvosi Hetilap
Volume144
Issue number3
Publication statusPublished - Jan 19 2003

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Methicillin Resistance
Staphylococcus
Virulence
Hungary
Coagulase
beta-Lactams
Methicillin-Resistant Staphylococcus aureus
Staphylococcus aureus
Inpatients
Anti-Bacterial Agents
Genes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A Staphylococcusok methicillinrezisztenciája és a kimutatásukra szolgáló módszer. / Fehérváriné, Tóth Mónika; Rozgonyi, F.

In: Orvosi Hetilap, Vol. 144, No. 3, 19.01.2003, p. 107-115.

Research output: Contribution to journalArticle

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