Metal ion and antioxidant alterations in leaves between different sexes of Ginkgo biloba L.

E. Stefanovits-Banyai, K. Szentmihályi, A. Hegedüs, Noémi Koczka, László Váli, Gabriella Taba, A. Blázovics

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

A comparative study was carried out to determine some valuable phytochemical components, macro- and microelement and redox parameters in leaves of male and female Ginkgo biloba trees and in extracts made from them. G. biloba extracts have become more popular as a therapeutic agent in the modern pharmacology in neurodegenerative diseases, in which increased brain metal levels can be observed and free radical reactions are involved. Macro- and microelement components, total phenol content, H-donating activity and reducing power as well as total scavenger capacity were determined in the samples. Well detectable differences were obtained for micro- and macroelement contents between male and female samples, but no toxic elements could be detected in the extracts. Male extracts contained more hazardous metals (e.g. Fe) compared to the female ones, while extracts from female leaves had higher levels of ions, which are known to have beneficial effects in neurodegenerative diseases. The ethanolic extracts of male leaves showed the highest H-donating activity, reducing power and total phenol content, as well as the best total scavenger activity. Ginkgo extracts due to the antioxidant properties may have favourable effects as dietary supplements in several neurodegenerative diseases, but this study draws the attention that critical evaluation is required in view of the potential hazard induced by their metal ion constitution. Our results lead us to the conclusion that although the aqueous extracts of female leaves are characterized by relatively lower antioxidant properties, they may be more eligible for these purposes due to their favourable metal ion constitution.

Original languageEnglish
Pages (from-to)1049-1056
Number of pages8
JournalLife Sciences
Volume78
Issue number10
DOIs
Publication statusPublished - Feb 2 2006

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Neurodegenerative diseases
Ginkgo biloba
Metal ions
Antioxidants
Metals
Ions
Phenol
Macros
Neurodegenerative Diseases
Dietary supplements
Free radical reactions
Constitution and Bylaws
Poisons
Phytochemicals
Brain
Hazards
Dietary Supplements
Oxidation-Reduction
Free Radicals
Pharmacology

Keywords

  • Antioxidants
  • Ginkgo biloba
  • Metal elements
  • Neurodegenerative diseases
  • Phenol

ASJC Scopus subject areas

  • Pharmacology

Cite this

Metal ion and antioxidant alterations in leaves between different sexes of Ginkgo biloba L. / Stefanovits-Banyai, E.; Szentmihályi, K.; Hegedüs, A.; Koczka, Noémi; Váli, László; Taba, Gabriella; Blázovics, A.

In: Life Sciences, Vol. 78, No. 10, 02.02.2006, p. 1049-1056.

Research output: Contribution to journalArticle

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