Metal-binding ability of Desferrioxamine B

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Abstract

The metal complex formation properties of the naturally-occurring hydroxamate type siderophore Desferrioxamine B is surveyed with special emphasis on its solution speciation. The most likely binding-modes of the complexes formed with this ambidentate ligand are also evaluated. A brief survey of the implications of metal chelation in the therapeutic role of DFB in the treatment of metal overloads is also given.

Original languageEnglish
Pages (from-to)385-403
Number of pages19
JournalJournal of Inclusion Phenomena and Molecular Recognition in Chemistry
Volume32
Issue number2-3
Publication statusPublished - Nov 1 1998

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Keywords

  • Desferrioxamine B
  • Metal complexes
  • Metal overload
  • Solution speciation

ASJC Scopus subject areas

  • Food Science
  • Chemistry(all)
  • Condensed Matter Physics

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