Metabolism of prostaglandin Fin early human placenta in vitro

D. Falkay, M. Sas

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The authors were investigating the metabolism of prostaglandin F2α in human early placenta, in in vitro incubation experiments. They have identified both major metabolites, 15-keto-PGPGFand 15-keto-13, 14 dehydro PGPGF. They have examined the change in the percentage of these, taken as a function of time. They have established that the main site of inactivating the endogenous PGPGF, is the early human placenta. They suppose that the considerable Pg-inactiviting effect of the placenta has a part which acts as a protecting mechanism in preventing the uterotonic influence of the endogenous prostaglandins.

Original languageEnglish
Pages (from-to)99-106
Number of pages8
JournalHormone Research in Paediatrics
Volume8
Issue number2
DOIs
Publication statusPublished - Jan 1 1977

Keywords

  • Human placenta
  • In vitro
  • Metabolism
  • Prostaglandin F

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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