Meningeoma es terhesseg

Translated title of the contribution: Meningioma and pregnancy

Bencze Janos, Varkoly Greta, T. Hortobágyi

Research output: Contribution to journalReview article

2 Citations (Scopus)


Meningiomas are one of the most frequent primary intracranial tumours, representing one-third of all intracranial- neoplasms. The vast majority of meningiomas are histologically benign, but recurrence and progression is quite frequent. They occur usually between the 6th and 7th decade, the female/male ratio is 3:2. Although rare in pregnancy, when occurring, they can cause serious, life-threatening complications due to rapid growth and unfavourable localisation. There are two dominant hypothesis explaining rapid growth in pregnancy: The role of hormonal effects and hemodynamic changes. Several studies tested these theories but none provided unequivocal answer probably because the pathomechanism is complex and multifactorial. We provide an overview of the pathomechanism of meningiomas in pregnancy with emphasis on data obtained by advanced neuropathological, molecular biological, bioinformatic, imaging and epidemiological methods. A better understanding of the processes leading to meningioma development and growth in pregnancy will help us to design personalized therapy and reduce morbidity and mortality.

Translated title of the contributionMeningioma and pregnancy
Original languageHungarian
Pages (from-to)220-224
Number of pages5
JournalIdeggyogyaszati Szemle
Issue number7-8
Publication statusPublished - Jul 30 2016

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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