Medication Effects and Sleep-Related Movement Disorders

Research output: Chapter in Book/Report/Conference proceedingChapter


Sleep-related movement disorders (SRMDs) including restless legs syndrome, periodic limb movement disorder, and sleep bruxism are sleep disorders which can have a high impact on sleep quality and in some cases also on sleep quantity. Pharmacological aggravation of these SRMDs is increasingly recognized. Medications including neuroleptics or other dopamine antagonists can induce or worsen these symptoms. Antidepressants and anticonvulsants may either relieve or aggravate SRMDs. The accurate diagnosis and appropriate change of medication(s) may substantially improve the quality of sleep as well as quality of life in this patient population. In the present work, we review the recent knowledge on the pharmacological exacerbation of SRMDs, and, where appropriate, potential therapeutic effects of these drugs are also described.

Original languageEnglish
Title of host publicationEncyclopedia of Sleep
PublisherElsevier Inc.
Number of pages4
ISBN (Electronic)9780123786111
ISBN (Print)9780123786104
Publication statusPublished - Jan 1 2013


  • Antidepressants
  • Bruxism
  • Medication side effect
  • Periodic limb movement in sleep
  • REM sleep without atonia
  • Restless legs syndrome
  • Sleep-related movement disorders

ASJC Scopus subject areas

  • Medicine (miscellaneous)

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