Medical treatment of Parkinson's disease: Today and the future

G. Gárdián, L. Vécsei

Research output: Contribution to journalReview article

24 Citations (Scopus)

Abstract

Idiopathic Parkinson's disease (PD) is the only neurodegenerative disorder for which highly effective symptomatic therapy is available. Although levodopa continues to be the gold standard of symptomatic efficacy for treatment of the cardinal motor features, its chronic use is associated with potentially disabling motor complications. This review provides a survey of the medication that can currently be utilized for pharmacological management of the motor and non-motor symptoms of Parkinson's disease. Focus is placed on recent and evolving studies evaluating symptomatic and neuroprotective effects of such medication, and on how such studies may impact the future management of Parkinson's disease.

Original languageEnglish
Pages (from-to)633-642
Number of pages10
JournalInternational Journal of Clinical Pharmacology and Therapeutics
Volume48
Issue number10
DOIs
Publication statusPublished - Oct 2010

Keywords

  • Kynurenine system
  • Neuroprotection
  • Parkinson's disease
  • Symptomatic therapy

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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