Medial temporal lobe epilepsy: Gender differences

J. Janszky, R. Schulz, I. Janszky, A. Ebner

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

The present study investigated the gender differences in medial temporal lobe epilepsy (MTLE) with regard to clinical history, seizure semiology, and EEG data. To avoid the influence of pathological and localisation differences, we included only MTLE patients with hippocampal sclerosis. Patients who had long term video EEG recordings with registered seizures and unilateral hippocampal sclerosis proved by high resolution MRI were included. There were 153 patients (86 women and 67 men) who met our inclusion criteria. The mean age of the patients was 33.5 years (range 16-59). The mean age at epilepsy onset was 10.8 years. Although there were more women than men, this difference was not significant (p=0.15). We found that male patients experienced generalised seizures significantly more often, and isolated auras significantly less often than female patients. Analysing EEG data, we found that a seizure pattern lateralised to the side of the hippocampal sclerosis occurred more often in female patients. In the logistic regression analysis, we found that all three factors were associated independently with gender. Odds ratio (OR) for female gender in patients with generalised seizures was 0.44 (95% confidence interval (95% CI) 0.21 to 0.92; p

Original languageEnglish
Pages (from-to)773-775
Number of pages3
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume75
Issue number5
DOIs
Publication statusPublished - May 2004

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Temporal Lobe Epilepsy
Seizures
Sclerosis
Electroencephalography
Epilepsy
Video Recording
Age of Onset
Logistic Models
Odds Ratio
Regression Analysis
Confidence Intervals

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health

Cite this

Medial temporal lobe epilepsy : Gender differences. / Janszky, J.; Schulz, R.; Janszky, I.; Ebner, A.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 75, No. 5, 05.2004, p. 773-775.

Research output: Contribution to journalArticle

Janszky, J. ; Schulz, R. ; Janszky, I. ; Ebner, A. / Medial temporal lobe epilepsy : Gender differences. In: Journal of Neurology, Neurosurgery and Psychiatry. 2004 ; Vol. 75, No. 5. pp. 773-775.
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