Measurement of complement components and alpha 1-antitrypsin during plasma exchange.

I. Csípő, Z. Bedö, S. Sipka, J. S. Lebedin, A. G. Chuchalin, G. Szegedi

Research output: Contribution to journalArticle

Abstract

Therapeutical plasma exchange can be carried out by using blood cell separators based upon centrifugation or in equipments with membranes. We investigated whether activation of the complement system took place in polyvinylchloride tubes used in the blood cell separator. We also examined the changes in the classical and alternative complement pathways by an analysis of functional haemolytic titers, as well as the levels of C4, C3D, C4, albumin and alpha 1-antitrypsin. No measurable activation of the complement system was found. The decreased levels of the C3, C3d, C4, albumin and alpha 1-antitrypsin in the sera after PE could be a consequence of the haemodilution.

Original languageEnglish
Pages (from-to)211-217
Number of pages7
JournalActa Medica Hungarica
Volume48
Issue number3-4
Publication statusPublished - 1991

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Complement C1
alpha 1-Antitrypsin
Plasma Exchange
Complement Activation
Albumins
Blood Cells
Classical Complement Pathway
Alternative Complement Pathway
Hemodilution
Centrifugation
Equipment and Supplies
Membranes
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Measurement of complement components and alpha 1-antitrypsin during plasma exchange. / Csípő, I.; Bedö, Z.; Sipka, S.; Lebedin, J. S.; Chuchalin, A. G.; Szegedi, G.

In: Acta Medica Hungarica, Vol. 48, No. 3-4, 1991, p. 211-217.

Research output: Contribution to journalArticle

Csípő, I. ; Bedö, Z. ; Sipka, S. ; Lebedin, J. S. ; Chuchalin, A. G. ; Szegedi, G. / Measurement of complement components and alpha 1-antitrypsin during plasma exchange. In: Acta Medica Hungarica. 1991 ; Vol. 48, No. 3-4. pp. 211-217.
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