Maternal plasma concentrations of magnesium, calcium, zinc and copper in normal and pathological pregnancies

P. Borella, A. Szilagyi, G. Than, I. Csaba, A. Giardino, F. Facchinetti

Research output: Contribution to journalArticle

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Abstract

In this study, plasma levels of magnesium, calcium, zinc and copper were simultaneously determined in pregnancies complicated by either abortion, intrauterine growth retardation (IUGR), diabetes or EPH (edema, proteinuria, hypertension) gestosis. The levels of the four cations in non-pregnant women and in healthy, pregnant women were also determined. Compared with controls, a significant decrease in magnesium, with increase of the Ca/Mg ratio, was found in spontaneous abortions, but not when patients had a successful continuation of pregnancy. In EPH gestosis, total calcium was reduced, with a significant decrease of the plasma Ca/Mg ratio. A slight, but significant, increase in plasma zinc was observed in women affected by either diabetes or IUGR, probably as a result of reduced zinc uptake by the fetus. In addition, higher copper levels were found in the pathologies studied, with the exception of missed abortions. The possible role of an altered Ca/Mg ratio homeostasis in relation to gestational pathologies is discussed.

Original languageEnglish
Pages (from-to)67-76
Number of pages10
JournalScience of the Total Environment
Volume99
Issue number1-2
DOIs
Publication statusPublished - Dec 1 1990

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pregnancy
Magnesium
Zinc
Copper
Calcium
magnesium
hypertension
diabetes
zinc
calcium
Pathology
pathology
Medical problems
copper
Plasmas
plasma
homeostasis
Cations
cation
Positive ions

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry

Cite this

Maternal plasma concentrations of magnesium, calcium, zinc and copper in normal and pathological pregnancies. / Borella, P.; Szilagyi, A.; Than, G.; Csaba, I.; Giardino, A.; Facchinetti, F.

In: Science of the Total Environment, Vol. 99, No. 1-2, 01.12.1990, p. 67-76.

Research output: Contribution to journalArticle

Borella, P. ; Szilagyi, A. ; Than, G. ; Csaba, I. ; Giardino, A. ; Facchinetti, F. / Maternal plasma concentrations of magnesium, calcium, zinc and copper in normal and pathological pregnancies. In: Science of the Total Environment. 1990 ; Vol. 99, No. 1-2. pp. 67-76.
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