Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn

Rita Bertalan, Laszlo Csabay, Anna Blazovics, Janos Rigo, Ibolya Varga, Zita Halasz, Erzsebet Toldy, Belema Boyle, Karoly Racz

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A 33-year-old primagravida with a history of polycystic ovary syndrome was referred because of symptoms of moderate hyperandrogenism. Serum hormone levels, measured regularly from the 7th week of pregnancy until delivery, showed very high increases of testosterone, androstenedione and estradiol. Ultrasound showed no evidence of adrenal or ovarian masses. She delivered a female newborn with normal female external genitalia. Umbilical cord hormone levels were normal, except for a modest increase of serum testosterone. After delivery the androgen levels of the mother returned to normal and the symptoms of hyperandrogenism were also slightly improved.

Original languageEnglish
Pages (from-to)581-583
Number of pages3
JournalGynecological Endocrinology
Volume23
Issue number10
DOIs
Publication statusPublished - Oct 1 2007

Keywords

  • Aromatase activity
  • Maternal hyperandrogenism
  • Pregnancy
  • Testosterone

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Obstetrics and Gynaecology

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