Massarilactones E-G, new metabolites from the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima

Karsten Krohn, Zia-Ullah, Hidayat Hussain, Ulrich Flörke, Barbara Schulz, Siegfried Draeger, Gennaro Pescitelli, Piero Salvadori, S. Antus, T. Kurtán

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Three new massarilactones E-G (1-3) and the massarilactone acetonide (4) were isolated from the ethyl acetate extract of the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima. Their structures were determined by analysis of the 1D and 2D NMR and mass spectroscopic data. The structure of massarilactones E (1) was confirmed by X-ray diffraction analysis, and its absolute configuration determined by the solid-state CD/TDDFT method.

Original languageEnglish
Pages (from-to)464-470
Number of pages7
JournalChirality
Volume19
Issue number6
DOIs
Publication statusPublished - 2007

Fingerprint

Metabolites
Fungi
X ray diffraction analysis
Nuclear magnetic resonance
X-Ray Diffraction
massarilactone E
massarilactone G
ethyl acetate

Keywords

  • Coniothyrium sp.
  • Fungal metabolites
  • Massarilactones
  • Solid-state CD-TDDFT method
  • Structure elucidation
  • X-ray analysis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Massarilactones E-G, new metabolites from the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima. / Krohn, Karsten; Zia-Ullah; Hussain, Hidayat; Flörke, Ulrich; Schulz, Barbara; Draeger, Siegfried; Pescitelli, Gennaro; Salvadori, Piero; Antus, S.; Kurtán, T.

In: Chirality, Vol. 19, No. 6, 2007, p. 464-470.

Research output: Contribution to journalArticle

Krohn, K, Zia-Ullah, Hussain, H, Flörke, U, Schulz, B, Draeger, S, Pescitelli, G, Salvadori, P, Antus, S & Kurtán, T 2007, 'Massarilactones E-G, new metabolites from the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima', Chirality, vol. 19, no. 6, pp. 464-470. https://doi.org/10.1002/chir.20402
Krohn, Karsten ; Zia-Ullah ; Hussain, Hidayat ; Flörke, Ulrich ; Schulz, Barbara ; Draeger, Siegfried ; Pescitelli, Gennaro ; Salvadori, Piero ; Antus, S. ; Kurtán, T. / Massarilactones E-G, new metabolites from the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima. In: Chirality. 2007 ; Vol. 19, No. 6. pp. 464-470.
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